Researcher
Bart De Strooper
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
- See also: Bart De Strooper (Flanders Institute for Biotechnology)
Affiliations
- Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven) (Lab)
Responsible
From1 Jan 2006 → Today - Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → Today - De Strooper Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → 31 Dec 2016
Projects
1 - 10 of 80
- MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's diseaseFrom16 May 2024 → TodayFunding: Foundations, funds and other with scientific goal
- Spatial Proteomics to Investigate the Cellular Phase of Alzheimer’s DiseaseFrom13 Feb 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A novel chimeric model investigating human neurological features in Alzheimer’s diseaseFrom1 Jan 2023 → TodayFunding: FWO fellowships
- A vicious Aβ oligomers-dependent neuron-microglia cycle fuels Alzheimer's DiseaseFrom1 Jan 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Human-mouse neuronal xenografts to study incipient Alzheimer’s Disease.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- The early microglia–neuron interactions in Alzheimer’s Disease and their modulation by immunotherapyFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's diseaseFrom1 May 2022 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Therapeutic targeting of pathogenic presynaptic Tau in human neurons in a chimeric Alzheimer’s Disease mouse modelFrom24 Jan 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Genetic Risk in Alzheimer's diseaseFrom14 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Functional characterization of human neurons in the human-mouse chimeric model for Alzheimer’s diseaseFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
271 - 280 of 330
- Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease(2011)
Authors: Bart De Strooper
Pages: 35 - 35 - The World of Dementia Beyond 2020(2011)
Authors: Bart De Strooper
Pages: 923 - 927 - Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease(2011)
Authors: Randall J Bateman, Paul S Aisen, Bart De Strooper, Nick C Fox, Cynthia A Lemere, John M Ringman, Stephen Salloway, Reisa A Sperling, Manfred Windisch, Chengjie Xiong
Pages: 35 - Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo(2011)
Authors: Ellen Jorissen, Bart De Strooper
Pages: 36 - The molecular study of Alzheimer's disease: The road to a causal treatment(2010)
Authors: Bart De Strooper
Pages: 1150 - 1155 - Neurotoxicity of Alzheimer's disease Abeta peptides is induced by small changes in the Abeta(42) to Abeta(40) ratio(2010)
Authors: Jef Rozenski, Geert Callewaert, Carmen Bartic, Rudi D'Hooge, Frederic Rousseau, Joost Schymkowitz, Bart De Strooper
Pages: 3408 - 3420 - Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration(2010)
Authors: Smaragda Papadopoulou, Bart De Strooper
Pages: 3959 - 3969 - Role of Pink1 in Parkinson's Disease and Mitochondrial Function: Pink1 Regulates Complex I Activity(2010)
Authors: VA Morais, Kathleen Craessaerts, An Snellinx, Lut Overbergh, AO Helbig, AJR Heck, Wim Mandemakers, W Wurst, Bart De Strooper
Pages: S625 - S625 - Study on Functional Redundancy of LRRK1 and LRRK2(2010)
Authors: Wim Mandemakers, Samer Matta, Vanessa Morais, An Snellinx, Bart De Strooper
Pages: S632 - S632 - LRRK2, a Gene Mutated in Parkinson's Disease, Promotes Synaptic Vesicle Endocytosis(2010)
Authors: Samer Matta, Vanessa Morais, Wim Mandemakers, Sven Vilain, Bart De Strooper, Patrik Verstreken
Pages: S631 - S632
Patents
1 - 10 of 10
- Γ-secretase stabilizing compound screening assay (Inventor)
- Gamma-secretase stabilizing compound screening assay (Inventor)
- Therapeutic agents for neurological and psychiatric disorders (Inventor)
- Therapeutic agents for neurological and psychiatric disorders (Inventor)
- Single domain antibodies capable of modulating bace activity (Inventor)
- Therapeutic agents for neurological and psychiatric disorders (Inventor)
- Single domain antibodies capable of modulating bace activity (Inventor)
- Gamma-secretase stabilizing compound screening assay (Inventor)
- Restoring phosphorylation of a novel pink1 substrate to treat parkinson's disease (Inventor)
- Restoring phosphorylation of a novel pink1 substrate to treat parkinson's disease (Inventor)