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Researcher
Bart De Strooper
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Member
From1 Jan 2017 → Today - Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → 30 Sep 2000
Projects
1 - 10 of 72
- To tackle Alzheimer's disease by targeting the presynaptic defects induced by tauFrom24 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Genetic Risk in Alzheimer's diseaseFrom14 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding the cellular phase of Alzheimer’s disease using spatial transcriptomicsFrom7 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Functional characterization of human neurons in the human-mouse chimeric model for Alzheimer’s diseaseFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Necroptosis pathway activation and its role in neuronal cell loss in Alzheimer's diseaseFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Resilience and vulnerability in the cellular phase of Alzheimer’s disease.From1 Oct 2021 → TodayFunding: BOF - Methusalem
- Resilience and vulnerability in the cellular phase of Alzheimer’s DiseaseFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The role of microglia in the pathogenesis of Alzheimer’s DiseaseFrom10 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the cellular phase of Alzheimer’s disease using spatial transcriptomics.From1 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Pyroptotic cell death in Alzheimer’s disease: pathological relevance and functional in vitro analysis.From16 Dec 2020 → TodayFunding: BOF - doctoral mandates
Publications
1 - 10 of 273
- AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model(2022)
Authors: Marika Marino, Zsuzsanna Callaerts-Végh, Jérôme Wahis, Maarten Dewilde, Adrian Liston, Bart De Strooper, Matthew Holt
Number of pages: 21 - Do we still need animals? Surveying the role of animal-free models in Alzheimer's and Parkinson's disease research(2022)
Authors: Bart De Strooper, Patrik Verstreken
Number of pages: 8 - The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics(2022)
Authors: Bart De Strooper
Pages: 306 - 318Number of pages: 13 - Editorial overview: Neurobiology of disease.(2022)
Authors: Bart De Strooper
Pages: iv - ix - Synaptic tau and synaptogyrin-3 are promising targets to tackle tauopathies.(2021)
Authors: Pablo Largo Barrientos, Valerie Uytterhoeven, Bart De Strooper
Pages: e054187 - The promise of microRNA-based therapies in Alzheimer's disease: challenges and perspectives(2021)
Authors: Hannah Walgrave, Bart De Strooper
Number of pages: 16 - Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease(2021)
Authors: Hannah Walgrave, Sriram Balusu, Nicola Thrupp, Zsuzsanna Callaerts-Végh, Rudi D'Hooge, Dietmar Rudolf Thal, Bart De Strooper
Pages: 1805 - +Number of pages: 26 - Bart De Strooper(2021)
Authors: Bart De Strooper
Pages: 3018 - 3021Number of pages: 4 - Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-beta plaques(2021)
Authors: Pranav Preman, Sebastian Munck, Dietmar Rudolf Thal, Bart De Strooper
Number of pages: 18 - The case for low-level BACE1 inhibition for the prevention of Alzheimer disease(2021)
Authors: Bart De Strooper
Pages: 703 - 714Number of pages: 12