Researcher
Bart De Geest
- Disciplines:Cardiology
Affiliations
- Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 12
- Lipoprotein-targeted therapies for lipotoxic heart diseaseFrom1 Jan 2017 → 1 Jan 2021Funding: BOF - Doctoral projects, BOF - doctoral mandates
- High-density lipoprotein infusion therapy for heart failure with reduced ejection fraction and heart failure with preserved ejection fraction.From1 Oct 2015 → 30 Sep 2018Funding: FWO fellowships
- Therapeutic potential of high-density lipoproteins in heart failure with reduced ejection fractionFrom1 Oct 2014 → 13 Nov 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- The impact of metabolic stress on ventricular remodelling, myocardial substrate metabolism, and lipotoxicity in pressure overload-induced cardiomyopathy.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- The impact of lipoproteins and of saturated fat on the development of heart failure: an experimental gene transfer and dietary intervention study.From1 Oct 2013 → 30 Sep 2017Funding: BOF - Concerted Research Project from 1994
- High density lipoprotein raising gene transfer strategies. Towards technological advances and new therapeutic niches.From1 Oct 2011 → 30 Sep 2014Funding: BOF - Other initiatives
- Evaluation of new predictors of transplant vasculopathy in heart transplant recipients.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- The role of homocysteine in atherothrombosis revisited.From1 Oct 2009 → 29 Feb 2012Funding: FWO fellowships
- The impact of lipoprotein on stem cells.From1 Oct 2009 → 30 Sep 2015Funding: FWO fellowships
- Towards new therapeutic areas for HDL-targeted interventionsFrom1 Oct 2009 → 30 Sep 2013Funding: IWT personal funding - strategic basic research grants
Publications
21 - 30 of 91
- Reconstituted HDL (Milano) Treatment Efficaciously Reverses Heart Failure with Preserved Ejection Fraction in Mice.(2018)
Authors: Mudit Mishra, Ilayaraja Muthuramu, Joseph Pierre Abou Msallem, Bart De Geest
- Successful treatment of established heart failure in mice with recombinant HDL (Milano).(2018)
Authors: Joseph Pierre Abou Msallem, Mudit Mishra, Md Ruhul Amin, Ilayaraja Muthuramu, Bart De Geest
Pages: 4167 - 4182 - Hepatocyte-restricted SR-BI gene transfer corrects cardiac dysfunction in SR-BI deficient mice and improves pressure overload-induced cardiomyopathy(2018)
Authors: Ilayaraja Muthuramu, Md Ruhul Amin, Joseph Pierre Abou Msallem, Mudit Mishra, Emma Louise Robinson, Bart De Geest
Pages: 2028 - 2040 - Selective HDL-Raising Human Apo A-I Gene Therapy Counteracts Cardiac Hypertrophy, Reduces Myocardial Fibrosis, and Improves Cardiac Function in Mice with Chronic Pressure Overload(2017)
Authors: Md Ruhul Amin, Ilayaraja Muthuramu, Joseph Pierre Abou Msallem, Mudit Mishra, Frank Jacobs, Bart De Geest
Pages: 1 - 14 - Selective HDL-Raising Human Apo A-I Gene Therapy Counteracts Cardiac Hypertrophy, Reduces Myocardial Fibrosis, and Improves Cardiac Function in Mice with Chronic Pressure Overload(2017)
Authors: Md Ruhul Amin, Ilayaraja Muthuramu, Joseph Pierre Abou Msallem, Mudit Mishra, Bart De Geest
Pages: 1 - 14 - Coconut Oil Aggravates Pressure Overload-Induced Cardiomyopathy without Inducing Obesity, Systemic Insulin Resistance, or Cardiac Steatosis(2017)
Authors: Ilayaraja Muthuramu, Md Ruhul Amin, Mudit Mishra, Olivier Gheysens, Paul P Van Veldhoven, Bart De Geest
Pages: 1 - 22 - Cholesterol lowering gene therapy counteracts the development of non-ischemic cardiomyopathy in mice(2017)
Authors: Ilayaraja Muthuramu, Md Ruhul Amin, Mudit Mishra, Joseph Pierre Abou Msallem, Tom Dresselaers, Uwe Himmelreich, Paul P Van Veldhoven, Olivier Gheysens, Bart De Geest
Pages: 2513 - 2525 - New perspectives on biological HDL-targeted therapies(2017)
Authors: Ilayaraja Muthuramu, Md Ruhul Amin, Bart De Geest
Pages: 793 - 796 - DIETARY SATURATED FATTY ACIDS AGGRAVATE PRESSURE OVERLOAD-INDUCED CARDIOMYOPATHY IN MICE IN THE ABSENCE OF CARDIAC STEATOSIS(2016)
Authors: Ilayaraja Muthuramu, R Amin, N Singh, A Postnov, Olivier Gheysens, Paul P Van Veldhoven, Bart De Geest
Pages: E119 - E119 - Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice(2016)
Authors: Frank Spillmann, Bart De Geest, Ilayaraja Muthuramu, Md Ruhul Amin, Kapka Miteva, Burkert Pieske, Carsten Tschöpe, Sophie Van Linthout