Researcher
Aurélie Crabbé
- Keywords:Host-pathogen interactions, Biofilm, Three-dimensional cell culture, Long disease, Anti-inflammatory therapy, Bacterial infections, Microbiome
- Disciplines:Inflammation, Innate immunity, Vaccinology, Biomarker discovery, Bacteriology, Respiratory medicine, Infectious diseases, In vitro testing, Microbiome
Affiliations
- Department of Pharmaceutical analysis (Department)
Member
From1 Oct 2014 → Today
Projects
1 - 10 of 15
- Fund Alphonse & Jean Forton and the Belgian CF Association muco.be: 'BEAT Pseudomonas: Beneficial bactEria AgainsT Pseudomonas'From1 Jan 2024 → TodayFunding: Foundations, funds and other with scientific goal
- Cystic fibrosis as a modulable model for host – microorganism interactions in airway disease.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- A nanobody-based anti-inflammatory treatment against Pseudomonas aeruginosa-induced inflammation in chronic lung diseases.From1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Exploring the anti-virulence potential of the lung microbiome in chronic airway infectionsFrom1 Nov 2021 → TodayFunding: FWO junior postdoctoral fellowship
- A nanobody-based anti-inflammatory treatment against Pseudomonas aeruginosa-induced inflammation in chronic lung diseasesFrom1 Oct 2021 → 31 Oct 2021Funding: BOF - doctoral mandates
- A nanobody-based anti-inflammatory treatment against pathogen-induced chronic lung inflammationFrom1 Oct 2021 → TodayFunding: BOF - projects
- Accelerating the valorisation of the BEAT inflammation technology, a microbiome-based biotherapeutic for chronic respiratory inflammatory diseases.From15 Oct 2020 → TodayFunding: IOF - technology validation in lab
- Research towards novel therapies against chronic lung infectionsFrom30 Sep 2020 → TodayFunding: BOF - projects
- Exploring the potential of personalized metabolic profiling to evaluate and boost antibiotic activityFrom1 Apr 2020 → 30 Sep 2021Funding: Other EU initiatives out of framework
Publications
21 - 30 of 39
- Antimicrobial tolerance and metabolic adaptations in microbial biofilms(2019)
Authors: Aurélie Crabbé, Peter Østrup Jensen, Thomas Bjarnsholt
Pages: 850 - 863 - Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics(2019)
Authors: Aurélie Crabbé, Lisa Ostyn, Sorien Staelens, Charlotte Rigauts, Martijn Risseeuw, Maarten Dhaenens, Simon Daled, Heleen Van Acker, Dieter Deforce, Serge Van Calenbergh, et al.
- The antimicrobial peptide lin-SB056-1 and its dendrimeric derivative prevent Pseudomonas aeruginosa biofilm formation in physiologically relevant models of chronic infections(2019)
Authors: Lucia Grassi, Giovanna Batoni, Lisa Ostyn, Petra Rigole, Sara Van den Bossche, Andrea C Rinaldi, Giuseppantonio Maisetta, Semih Esin, Tom Coenye, Aurélie Crabbé
- In vitro evolution of Pseudomonas aeruginosa AA2 biofilms in the presence of cystic fibrosis lung microbiome members(2019)
Authors: Eva Vandeplassche, Andrea Sass, Astrid Lemarcq, Ajai Dandekar, Aurélie Crabbé
- Influence of the lung microbiome on antibiotic susceptibility of cystic fibrosis pathogens(2019)
Authors: Eva Vandeplassche, Sarah Tavernier, Tom Coenye, Aurélie Crabbé
- Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa(2018)
Authors: Graciela Rodriguez-Sevilla, Charlotte Rigauts, Eva Vandeplassche, Lisa Ostyn, Ignacio Mahillo-Fernandez, Jaime Esteban, Concepcion Perez-Jorge Peremarch, Aurélie Crabbé
- Coumarin reduces virulence and biofilm formation in Pseudomonas aeruginosa by affecting quorum sensing, type III secretion and C-di-GMP levels(2018)
Authors: Yunhui Zhang, Andrea Sass, Heleen Van Acker, Jasper Wille, Bruno Verhasselt, Filip Van Nieuwerburgh, Volkhard Kaever, Aurélie Crabbé
- Modeling host-pathogen interactions in the context of the microenvironment : three-dimensional cell culture comes of agee(2018)
Authors: Jennifer Barrila, Aurélie Crabbé, Jiseon Yang, Karla Franco, Seth D. Nydam, Rebecca J. Forsyth, Richard R. Davis, Sandhya Gangaraju, C. Mark Ott, Carolyn B. Coyne, et al.
- Decreased susceptibility of Streptococcus anginosus to vancomycin in a multispecies biofilm is due to increased thickness of the cell wall(2018)
Authors: Sarah Tavernier, Andrea Sass, Michiel De Bruyne, Aurélie Crabbé, Ilse Vandecandelaere, Filip Van Nieuwerburgh
Pages: 2323 - 2330 - Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models(2017)
Authors: Freija Van den Driessche, Bieke Vanhoutte, Gilles Brackman, Aurélie Crabbé, Jurgen Vercruysse, Glenn Verstraete, Davie Cappoen, Chris Vervaet, Paul Cos