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Researcher
Arthur Van Aerschot
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Sep 2022
Projects
1 - 10 of 19
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of new antimicrobials: Rational design of polyomavirus and mycobacterial inhibitorsFrom1 Oct 2019 → 23 Nov 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of a comprehensive platform for targeting redox homeostasis in Mycobacterium tuberculosis.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Structure-guided design and development of antivirals targeting BK polyomavirus capsidFrom1 Oct 2018 → 30 Sep 2023Funding: IOF - Industrial Research Fund, Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- Tyrosine-tRNA synthetase as target for the development of new antibacterial lead structuresFrom1 Sep 2018 → 1 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- In vivo molecular ion channel imaging.From1 May 2018 → 30 Sep 2022Funding: FWO Odysseus
- Structure-based design of new antitubercular medicinesFrom1 Oct 2017 → 30 Sep 2019Funding: BOF - Bilateral scientific cooperation
- Structural Characterization of Aminoacyl-tRNA Synthetase Inhibitors as Antibiotics and Tools for Enzyme Mechanistic StudiesFrom1 Oct 2016 → 23 Sep 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- High throughput analysis of biomolecular interactionsFrom1 May 2016 → 30 Apr 2020Funding: FWO Medium Size Research Infrastructure
- Synthesis and biological evaluation of albomycin and aminoacyl sulfonamide analogues as potential aaRS inhibitors.From1 Oct 2015 → 30 Sep 2018Funding: FWO fellowships
Publications
41 - 50 of 98
- Synthesis and evaluation of imidazole-4,5- and pyrazine-2,3-dicarboxamides targeting dengue and yellow fever virus(2014)
Authors: Joanna Zmurko, Suzanne Kaptein, Jef Rozenski, Johan Neyts, Arthur Van Aerschot
Pages: 529 - 539 - Synthesis and biological evaluation of novel nucleoside analogues and heterocycles targeting Flavivirus infections(2014)
Authors: Arthur Van Aerschot
Number of pages: 132 - A Trojan-Horse Strategy for Antimicrobial Therapy(2014)
Authors: Bharat Gadakh, Arthur Van Aerschot
- In search of Flavivirus inhibitors part 2: Tritylated, diphenylmethylated and other alkylated nucleoside analogues(2014)
Authors: Milind Saudi, Joanna Zmurko, Suzanne Kaptein, Jef Rozenski, Johan Neyts, Arthur Van Aerschot
Pages: 98 - 109 - Exploring the substrate promiscuity of an antibiotic inactivating enzyme(2014)
Authors: Bharat Gadakh, Arthur Van Aerschot
Pages: 1567 - 1570 - The RimL Transacetylase Provides Resistance to Translation Inhibitor Microcin C(2014)
Authors: Arthur Van Aerschot
Pages: 3377 - 3385 - Base substituted 5 '-O-(N-isoleucyl)sulfamoyl nucleoside analogues as potential antibacterial agents(2014)
Authors: Bharat Gadakh, Eveline Lescrinier, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Pages: 2875 - 2886 - In search of flavivirus inhibitors: Evaluation of different tritylated nucleoside analogues(2013)
Authors: Yannick Debing, Tine De Burghgraeve, Joanna Zmurko, Milind Saudi, Jef Rozenski, Johan Neyts, Arthur Van Aerschot
Pages: 249 - 255 - Enantiomeric Selection Properties of β-homoDNA: Enhanced Pairing for Heterochiral Complexes(2013)
Authors: Mathy Froeyen, Arthur Van Aerschot, Piet Herdewyn
Pages: 6662 - 6665 - 3',5'Di-O-trityluridine inhibits in vitro flavivirus replication(2013)
Authors: Tine De Burghgraeve, Suzanne Kaptein, Pieter Leyssen, Yannick Debing, Arthur Van Aerschot, Johan Neyts
Pages: 242 - 247