Researcher
Arthur Van Aerschot
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Sep 2022
Projects
1 - 10 of 19
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of new antimicrobials: Rational design of polyomavirus and mycobacterial inhibitorsFrom1 Oct 2019 → 23 Nov 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of a comprehensive platform for targeting redox homeostasis in Mycobacterium tuberculosis.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Structure-guided design and development of antivirals targeting BK polyomavirus capsidFrom1 Oct 2018 → 30 Sep 2023Funding: IOF - Industrial Research Fund, Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- Tyrosine-tRNA synthetase as target for the development of new antibacterial lead structuresFrom1 Sep 2018 → 1 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- In vivo molecular ion channel imaging.From1 May 2018 → 30 Sep 2022Funding: FWO Odysseus
- Structure-based design of new antitubercular medicinesFrom1 Oct 2017 → 30 Sep 2019Funding: BOF - Bilateral scientific cooperation
- Structural Characterization of Aminoacyl-tRNA Synthetase Inhibitors as Antibiotics and Tools for Enzyme Mechanistic StudiesFrom1 Oct 2016 → 23 Sep 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- High throughput analysis of biomolecular interactionsFrom1 May 2016 → 30 Apr 2020Funding: FWO Medium Size Research Infrastructure
- Synthesis and biological evaluation of albomycin and aminoacyl sulfonamide analogues as potential aaRS inhibitors.From1 Oct 2015 → 30 Sep 2018Funding: FWO fellowships
Publications
21 - 30 of 98
- Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies(2019)
Authors: Flore De Wit, Eveline Lescrinier, Zeger Debyser, Arthur Van Aerschot
- The search for new antibiotics: evaluation of inhibitory ligands of tRNA synthetases based on a nucleoside scaffold(2018)
Authors: Baole Zhang, Arthur Van Aerschot
- Family wide analysis of aminoacyl-sulfamoyl-3-deaza-adenosine analogues as inhibitors of aminoacyl-tRNA synthetases(2018)
Authors: Baole Zhang, Steff De Graef, Manesh Nautiyal, Luping Pang, Bharat Gadakh, Mathy Froeyen, Lieve Vanmellaert, Sergei Strelkov, Stephen Weeks, Arthur Van Aerschot
Pages: 384 - 396 - Direct on-chip DNA synthesis using electrochemically modified gold electrodes as solid support(2018)
Authors: Karen Levrie, Pol Van Dorpe, Liesbet Lagae, Chris Van Hoof, Arthur Van Aerschot, Tim Stakenborg
- Different positions of amide side chains on the benzimidazo[1,2-: A] quinoline skeleton strongly influence biological activity(2018)
Authors: Sandra Liekens, Arthur Van Aerschot, Peter Vervaeke, Bharat Gadakh
Pages: 7096 - 7104 - Spectroscopic investigation of the formation and disruption of hydrogen bonds in pharmaceutical semicrystalline dispersions(2017)
Authors: Arthur Van Aerschot, Jan Van Humbeeck, Guy Van den Mooter
Pages: 1726 - 1741 - High resolution multiplexing for DNA arrays using a multi-electrode chip(2017)
Authors: Pol Van Dorpe, Liesbet Lagae, Chris Van Hoof, Arthur Van Aerschot
Pages: 945 - 946 - Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors(2017)
Authors: Suzanne Kaptein, Johan Neyts, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Pages: 101 - 109 - A Trojan-horse peptide-carboxymethyl-cytidine antibiotic from Bacillus amyloliquefaciens(2016)
Authors: Manesh Nautiyal, Arthur Van Aerschot
Pages: 15690 - 15698 - Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus(2016)
Authors: Joanna Zmurko, Suzanne Kaptein, Jef Rozenski, Bharat Gadakh, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Arthur Van Aerschot
Pages: 158 - 168