Researcher
Annemieke Madder
- Keywords:protein modification, peptides, oligonucleotides, bioorthogonal conjugation
- Disciplines:Organic chemical synthesis, Food chemistry, Bio-organic chemistry, Drug discovery and development not elsewhere classified, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 1993 → Today
Projects
1 - 10 of 61
- Antibody-oligonucleotide conjugation for cellular delivery of oligonucleotidesFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Furan and porphyrin containing crosslinking ligands for covalent stabilisation of G quadruplexes as cell-permeable anti-cancer aptamersFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Synthetic antibody (SynAb) receptors for the detection and isolation of cyclic depsipeptide (CDP) toxins in food samples.From1 Apr 2023 → TodayFunding: BOF - various, Horizon Europe - Marie Skłodowska-Curie-actions
- A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN)From1 Jan 2023 → TodayFunding: BOF - iBOF
- Routine NMR Analysis Equipment for Small Molecule Characterisation.From15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Oct 2022 → 31 Oct 2022Funding: BOF - doctoral mandates
Publications
41 - 50 of 239
- Disruption of endocytosis through chemical inhibition of clathrin heavy chain function(2019)
Authors: Wim Dejonghe, Isha Sharma, Bram Denoo, Steven De Munck, Qing Lu, Kiril Mishev, Haydar Bulut, Evelien Mylle, Riet De Rycke, Mina Vasileva, et al.
Pages: 641 - 649 - Pyrrole-mediated peptide cyclization identified through genetically reprogrammed peptide synthesis(2018)
Authors: Klaas Decoene, Willem Vannecke, Toby Passioura, Hiroaki Suga, Annemieke Madder
- Nonselective chemical inhibition of Sec7 domain-containing ARF GTPase exchange factors(2018)
Authors: Kiril Mishev, Qing Lu, Bram Denoo, Francois Peurois, Wim Dejonghe, Jan Hullaert, Sjef Boeren, Marine Bretou, Steven De Munck, Isha Sharma, et al.
Pages: 2573 - 2593 - Design and syntheses of highly potent teixobactin analogues against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) in vitro and in vivo(2018)
Authors: Anish Parmar, Rajamani Lakshminarayanan, Abhishek Iyer, Venkatesh Mayandi, Eunice Tze Leng Goh, Daniel G Lloyd, Madhavi Latha S Chalasani, Navin Kumar Verma, Stephen H Prior, Roger W Beuerman, et al.
Pages: 2009 - 2017 - Templated DNA cross-linking : towards a non-invasive singlet-oxygen-based triggering method(2018)
Authors: Nathalie De Laet, Eva Marina Llamas Garcinuño, Annemieke Madder
Pages: 575 - 579 - Concerted biophysical and biological evaluation of Pseudomonas lipopeptides as a premise to unlock their application potential(2018)Volume: 24
Authors: José Martins, Yentl Verleysen, Benjámin Kovács, Vic De Roo, Christophe Ampe, Annemieke Madder, Niels Geudens
Pages: S61 - S61 - A thiolactone strategy for straightforward synthesis of disulfide-linked side-chain-to-tail cyclic peptides featuring an N-terminal modification handle(2018)
Authors: Dorien Van Lysebetten, Stefania Felissati, Eirini Antonatou, Lieselot Carrette, Pieter Espeel, Evelien Focquet, Filip Du Prez, Annemieke Madder
Pages: 641 - 646 - Oxygen consumption rate analysis of mitochondrial dysfunction caused by Bacillus cereus cereulide in Caco-2 and HepG2 cells(2018)
Authors: Marlies Decleer, Jelena Jovanovic, Anita Vakula, Bozidar Udovicki, Rock-Seth EK Agoua, Annemieke Madder, Sarah De Saeger, Andreja Rajkovic
- Development of a synthetic receptor for the food toxin beauvericin : a tale of carbazole and steroids(2018)
Authors: Vincent Ornelis, Andreja Rajkovic, Benedikt Sas, Annemieke Madder
Pages: 6368 - 6371 - Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization(2018)
Authors: Lars Verdonck, Dieter Buyst, Anne-Mare de Vries, Vicky Gheerardijn, Annemieke Madder, José Martins
Pages: 11671 - 11686
Patents
1 - 10 of 10
- Hydrogel-forming composition for controlled released (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Hydrogel-forming peptides (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- Hydrogel-forming peptides (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Synthetic receptors for ionophoric compounds (Inventor)