Researcher
Annemieke Madder
- Keywords:protein modification, peptides, oligonucleotides, bioorthogonal conjugation
- Disciplines:Organic chemical synthesis, Food chemistry, Bio-organic chemistry, Drug discovery and development not elsewhere classified, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 1993 → Today
Projects
1 - 10 of 61
- Antibody-oligonucleotide conjugation for cellular delivery of oligonucleotidesFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Furan and porphyrin containing crosslinking ligands for covalent stabilisation of G quadruplexes as cell-permeable anti-cancer aptamersFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Synthetic antibody (SynAb) receptors for the detection and isolation of cyclic depsipeptide (CDP) toxins in food samples.From1 Apr 2023 → TodayFunding: BOF - various, Horizon Europe - Marie Skłodowska-Curie-actions
- A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN)From1 Jan 2023 → TodayFunding: BOF - iBOF
- Routine NMR Analysis Equipment for Small Molecule Characterisation.From15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Oct 2022 → 31 Oct 2022Funding: BOF - doctoral mandates
Publications
21 - 30 of 239
- Beyond small molecules : targeting G-quadruplex structures with oligonucleotides and their analogues(2021)
Authors: Enrico Cadoni, Lessandro De Paepe, Alex Manicardi, Annemieke Madder
Pages: 6638 - 6659 - Hydrolysis of 5-methylfuran-2-yl to 2,5-dioxopentanyl allows for stable bio-orthogonal proximity-induced ligation(2021)
Authors: Alex Manicardi, Enrico Cadoni, Annemieke Madder
- Crosslinker-modified nucleic acid probes for improved target identification and biomarker detection(2021)
Authors: Joke Elskens, Annemieke Madder
Pages: 410 - 422 - 5-Hydroxy-pyrrolone based building blocks as maleimide alternatives for protein bioconjugation and single-site multi-functionalization(2021)
Authors: Ewout De Geyter, Eirini Antonatou, Dimitris Kalaitzakis, Sabina Smolen, Abhishek Iyer, Laure Tack, Emiel Ongenae, Georgios Vassilikogiannakis, Annemieke Madder
Pages: 5246 - 5252 - Bacillus cereus food intoxication and toxicoinfection(2021)
Authors: Vincent Ornelis, Annemieke Madder, Andreja Rajkovic
Pages: 3719 - 3761 - Detection of toxins involved in foodborne diseases caused by Gram-positive bacteria(2020)
Authors: Andreja Rajkovic, Silvia Monteiro, Marlies Decleer, Mirjana Andjelkovic, Astrid Foubert, Natalia Beloglazova, Varvara Tsilla, Benedikt Sas, Annemieke Madder
Pages: 1605 - 1657 - GOLVEN peptide signalling through RGI receptors and MPK6 restricts asymmetric cell division during lateral root initiation(2020)
Authors: Ana Fernandez Salina, Nick Vangheluwe, Ke Xu, Joris Jourquin, Lucas Alves Neubus Claus, Stefania Morales, Boris Parizot, Hugues De Gernier, Qiaozhi Yu, Andrzej Drozdzecki, et al.
Pages: 533 - 543 - Do aptamers always bind? : the need for a multifaceted analytical approach when remonstrating binding affinity between aptamer and low molecular weight compounds(2020)
Authors: Fabio Bottari, Elise Daems, Anne-Mare de Vries, Pieter Van Wielendaele, Stanislav Trashin, Ronny Blust, Frank Sobott, Annemieke Madder, José Martins, Karolien De Wael
Pages: 19622 - 19630 - Nanobody click chemistry for convenient site-specific fluorescent labelling, single step immunocytochemistry and delivery into living cells by photoporation and live cell imaging(2020)
Authors: Tim Hebbrecht, Jing Liu, Gaelle Boddin, Chloé Van Leene, Klaas Decoene, Annemieke Madder, Kevin Braeckmans, Jan Gettemans
Pages: 33 - 43 - Chemical modification of aptamers for increased binding affinity in diagnostic applications : current status and future prospects(2020)
Authors: Jan Elskens, Joke Elskens, Annemieke Madder
Patents
1 - 10 of 10
- Hydrogel-forming composition for controlled released (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Hydrogel-forming peptides (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- Hydrogel-forming peptides (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Synthetic receptors for ionophoric compounds (Inventor)