Researcher
Annemieke Madder
- Keywords:protein modification, peptides, oligonucleotides, bioorthogonal conjugation
- Disciplines:Organic chemical synthesis, Food chemistry, Bio-organic chemistry, Drug discovery and development not elsewhere classified, Biomolecular modelling and design, Medicinal and biomolecular chemistry not elsewhere classified
Affiliations
- Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 1993 → Today
Projects
1 - 10 of 61
- Antibody-oligonucleotide conjugation for cellular delivery of oligonucleotidesFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Furan and porphyrin containing crosslinking ligands for covalent stabilisation of G quadruplexes as cell-permeable anti-cancer aptamersFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- A combined structure-activity and biophysical investigation of the cyclic lipopeptide tolaasin, the virulence factor causing brown blotch diseaseFrom1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Synthetic antibody (SynAb) receptors for the detection and isolation of cyclic depsipeptide (CDP) toxins in food samples.From1 Apr 2023 → TodayFunding: BOF - various, Horizon Europe - Marie Skłodowska-Curie-actions
- A new photoelectrochemical singlet oxygen-based detection platform for a panel of cancer biomarkers in tissue and liquid biopsies (SOCAN)From1 Jan 2023 → TodayFunding: BOF - iBOF
- Routine NMR Analysis Equipment for Small Molecule Characterisation.From15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Crosslinking Aptamers for Covalent Protein TargetingFrom1 Oct 2022 → 31 Oct 2022Funding: BOF - doctoral mandates
Publications
11 - 20 of 239
- Equipping coiled-coil peptide dimers with furan warheads reveals novel cross-link partners(2022)
Authors: Laia Miret Casals, Sander Van De Putte, Dorien Aerssens, Julien Diharce, Pascal Bonnet, Annemieke Madder
- Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release(2022)
Authors: Julie Heremans, Lucie Chevillard, Morgane Mannes, Jessica Mangialetto, Kaat Leroy, Jacinta F. White, Arthur Lamouroux, Mathieu Vinken, James Gardiner, Bruno Van Mele, et al.
Pages: 514 - 524 - GlyConnect-Ugi : site-selective, multi-component glycoprotein conjugations through GlycoDelete expressed glycans(2022)
Authors: Karel Thooft, Wander Van Breedam, Francis Santens, Sandrine Vanmarcke, Simon Devos, Annemieke Madder
Pages: 464 - 471 - A photosensitized singlet oxygen ( 1 O 2) toolbox for bio-organic applications : tailoring 1 O 2 generation for DNA and protein labelling, targeting and biosensing(2022)
Authors: Dorien Aerssens, Enrico Cadoni, Laure Tack, Annemieke Madder
- Synthesis and structure-activity relationship of peptide nucleic acid probes with improved interstrand-crosslinking abilities: application to biotin-mediated RNA-pulldown(2022)
Authors: Enrico Cadoni, Francesca Pennati, Penthip Muangkaew, Joke Elskens, Annemieke Madder, Alex Manicardi
Pages: 1129 - 1143 - Novel electrochemiluminescent assay for the aptamer-based detection of testosterone(2022)
Authors: Rocio Canovas, Elise Daems, Rui Campos, Sofie Schellinck, Annemieke Madder, José Martins, Frank Sobott, Karolien De Wael
- An nuclear magnetic resonance fingerprint matching approach for the identification and structural re-evaluation of Pseudomonas lipopeptides(2022)
Authors: Vic De Roo, Yentl Verleysen, Benjámin Kovács, Matthias De Vleeschouwer, Penthip Muangkaew, Léa Girard, Monica Höfte, René De Mot, Annemieke Madder, Niels Geudens, et al.
- Furan warheads for covalent trapping of weak protein-protein interactions : cross-linking of thymosin β4 to actin(2021)
Authors: Laia Miret Casals, Willem Vannecke, Kurt Hoogewijs, Gianluca Arauz-Garofalo, Marina Gay, Mireia Diaz-Lobo, Marta Vilaseca, Christophe Ampe, Marleen Van Troys, Annemieke Madder
Pages: 6054 - 6057 - Teaching photosensitizers a new trick : red light-triggered G-quadruplex alkylation by ligand co-localization(2021)
Authors: Enrico Cadoni, Alex Manicardi, Mathieu Fossepre, Kaat Heirwegh, Mathieu Surin, Annemieke Madder
Pages: 1010 - 1013 - Towards the understanding of halogenation in peptide hydrogels : a quantum chemical approach(2021)
Authors: Tom Bettens, Valentin Lacanau, Ruben Van Lommel, Tess De Maeseneer, Wouter Vandeplassche, Jolien Bertouille, Joost Brancart, Thomas M. A. Barlow, Tatiana Woller, Niko Van den Brande, et al.
Pages: 4792 - 4803
Patents
1 - 10 of 10
- Hydrogel-forming composition for controlled released (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Hydrogel-forming peptides (Inventor)
- BIOCONJUGATION REAGENT AND METHODS (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- Hydrogel-forming peptides (Inventor)
- Methods for covalently binding a cell surface protein and a ligand (Inventor)
- METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT (Inventor)
- Synthetic receptors for ionophoric compounds (Inventor)