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Researcher
Anna Sablina
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
- See also: Anna Sablina (Flanders Institute for Biotechnology)
Affiliations
- Laboratory for Mechanisms of Cell Transformation (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - Laboratory for Mechanisms of Cell Transformation (VIB-KU Leuven) (Division)
Member
From1 Jan 2017 → Today - Sablina Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Human Genetics (Department)
Member
From16 Apr 2009 → 31 Dec 2016
Projects
1 - 10 of 20
- Molecular structure and pharmacological activation of LZTR1 towards novel anticancer therapiesFrom20 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping the functional role of the low copy repeats in the phenotypic variability of the 22q11.2 Deletion SyndromeFrom27 Jan 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Optimize single -cell sequence approaches in PDACFrom14 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Micropeptides as novel biomarkers and precision medicine targets in cancerFrom26 Sep 2022 → 26 Jan 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Micropeptides in head and neck cancerFrom9 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting KRAS proteoastasis to develop personalized therapies for lung cancer patientsFrom1 Oct 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Micropeptides as potential targets for cancer treatment in Lung AdenocarcinomaFrom18 Nov 2020 → 1 Jun 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of LZTR1 in cancer development and progressionFrom10 Apr 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Alterations in RAS interactome triggered by ubiquitinationFrom1 Dec 2019 → 1 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Nanobody-based approach to inhibit RAS activity by modultating its interactomeFrom1 Jan 2019 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 49
- Targeted STAT1 therapy for LZTR1-driven peripheral nerve sheath tumor(2023)
Authors: Christopher Cawthorne, Willy Gsell, Greetje Vande Velde, Christophe Deroose, Koen Van Laere, Uwe Himmelreich, Raj Sewduth, Anna Sablina
Pages: 1386 - 1390 - Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination.(2023)
Authors: Raj Sewduth, Elizabeth Jones, Anna Sablina
- The deubiquitinase OTUB1 governs lung cancer cell fitness by modulating proteostasis of OXPHOS proteins(2023)
Authors: Aidana Sheryazdanova, Anna Sablina
- A bimodal mechanism of RAS inactivation by monoubiquitination(2023)
Authors: Anna Sablina
- A bimodal mechanism of RAS inactivation by monoubiquitination(2023)
Authors: Anna Sablina
- Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding(2023)
Authors: Maxim De Schepper, Tatjana Geukens, Stefaan Soenen, Christine Desmedt, Colinda Scheele, Anna Sablina, Max Mazzone
- Editorial overview: Folding and binding(2022)
Authors: Anna Sablina
- The regulation of the protein interaction network by monoubiquitination(2022)
Authors: Anna Sablina
- PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition(2021)
Authors: Bob Meeusen, Emanuela Elsa Cortesi, Judit Domènech Omella, Anna Sablina, Juan-Jose Ventura, Veerle Janssens
Pages: 57 - 67 - Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development(2021)
Authors: Raj Sewduth, Maria Francesca Baietti, Nathan Criem, Anna Sablina
Pages: 4218 - 4229