Researcher
Aleksandra Siekierska
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From14 Mar 2022 → Today - Molecular Biodiscovery (Division)
Member
From1 Apr 2013 → 13 Mar 2022
Projects
1 - 1 of 1
- In vivo modeling of epileptic encephalopathies caused by mutations in aminoacyl-tRNA synthetases in zebrafish.From1 Oct 2015 → 30 Sep 2018Funding: FWO fellowships
Publications
1 - 10 of 18
- Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor(2022)
Authors: Aleksandra Siekierska, Peter de Witte, Daniëlle Copmans
- Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities(2022)
Authors: Ann-Sofie De Meulemeester, Lise Heylen, Aleksandra Siekierska, Peter de Witte
- Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery(2022)
Authors: Lise Heylen, Michèle Partoens, Peter de Witte, Aleksandra Siekierska
- Ethylenediamine derivatives efficiently react with oxidized RNA 3 ' ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation(2022)
Authors: Aleksandra Siekierska, Peter de Witte
- Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish(2021)
Authors: Lise Heylen, Ann-Sofie De Meulemeester, Daniëlle Copmans, Youcef Kazwiny, Pieter Vanden Berghe, Peter de Witte, Aleksandra Siekierska
- Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish(2021)
Authors: Michèle Partoens, Ann-Sofie De Meulemeester, Peter de Witte, Aleksandra Siekierska
- G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling(2021)
Authors: Ann-Sofie De Meulemeester, Aleksandra Siekierska, Peter de Witte
Pages: 655 - + - mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis(2017)
Authors: Chloë Scheldeman, Aleksandra Siekierska, Daniëlle Copmans, Lieven Lagae, Peter de Witte
Pages: 225 - 237 - RECESSIVE VARIANTS IN VARS CAUSE A CLINICAL SYNDROME WITH SEVERE DEVELOPMENTAL DELAY, EPILEPSY AND MICROCEPHALY(2017)
Authors: Aleksandra Siekierska, H Stamberger, J Sourbron, T Deconinck, A Kecskes, S Oprescu, Q Waisfisz, K Helbig, K Hardies, D Shinde, et al.
Pages: S177 - S177 - Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy(2017)
Authors: Borbála Hunyadi, Aleksandra Siekierska, Jo Sourbron, Daniëlle Copmans, Peter de Witte
Pages: 13 - 24