Researcher
Alejandro Sifrim
- Disciplines:Genetics, Systems biology, Molecular and cell biology, Medical imaging and therapy, Other paramedical sciences
Affiliations
- Laboratory of Multi-omic Integrative Bioinformatics (Division)
Responsible
From1 Sep 2020 → Today - Department of Human Genetics (Department)
Member
From1 Sep 2020 → Today - Dynamical Systems, Signal Processing and Data Analytics (STADIUS) (Division)
Member
From1 Aug 2020 → 16 Oct 2016 - Laboratory of Reproductive Genomics (Division)
Member
From17 Oct 2016 → 31 Aug 2020
Projects
1 - 10 of 17
- A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex DiseaseFrom1 Jan 2024 → TodayFunding: BOF - projects
- Machine Learning for Single-Molecule and Single-cell Multiomics to Bridge Genotype and Phenotype.From17 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding vulnerability in ALS using multi-omicsFrom27 Jun 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An AI-driven study of mRNA subcellular localization using highly-multiplexed super-resolution in situ transcriptomicsFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Single-cell and spatial multi-omics for biomedicineFrom1 Oct 2022 → TodayFunding: IOF - mandates
- Single-objective light sheet instrument for fast and highthroughput imaging of 3D tissueFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- COLUMBO: Engineered CRISPR toolbox for revolutionizing single-cell genome imaging in embryogenesis and oncologyFrom1 Oct 2021 → TodayFunding: BOF - projects
- Automated characterization of cellular morphology and subcellular expression patterns using spatial transcriptomics and deep neural networksFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Development of multimodal deep neural networks for spatial multi-omics data fusionFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Disease Mechanisms in ALS [a Single Nuclei Sequencing Study of Patient-derived Material]From22 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 53
- Early lineage segregation of multipotent embryonic mammary gland progenitors (vol 20, pg 666, 2018)(2018)
Authors: Aline Wuidart, Alejandro Sifrim, Marco Fioramonti, Shigeru Matsumura, Audrey Brisebarre, Daniel Brown, Alessia Centonze, Anne Dannau, Christine Dubois, Alexandra Van Keymeulen, et al.
Pages: 1099 - 1099 - Early lineage segregation of multipotent embryonic mammary gland progenitors(2018)
Authors: Alejandro Sifrim, Daniel Brown, Thierry Voet
- Identification of the tumour transition states occurring during EMT(2018)
Authors: Alejandro Sifrim, Daniel Brown, Chris Marine, Thierry Voet
Pages: 463 - 468 - De novo mutations in regulatory elements in neurodevelopmental disorders(2018)
Authors: Patrick J Short, Jeremy F McRae, Giuseppe Gallone, Alejandro Sifrim, Hyejung Won, Daniel H Geschwind, Caroline F Wright, Helen V Firth, David R FitzPatrick, Jeffrey C Barrett, et al.
Pages: 611 - 616 - Detection of structural mosaicism from targeted and whole-genome sequencing data(2017)
Authors: Daniel A King, Alejandro Sifrim, Tomas W Fitzgerald, Raheleh Rahbari, Emma Hobson, Tessa Homfray, Sahar Mansour, Sarju G Mehta, Mohammed Shehla, Susan E Tomkins, et al.
Pages: 1704 - 1714 - Clinical and molecular consequences of disease-associated de novo mutations in SATB2(2017)
Authors: Hemant Bengani, Mark Handley, Mohsan Alvi, Rita Ibitoye, Melissa Lees, Sally Ann Lynch, Wayne Lam, Madeleine Fannemel, Ann Nordgren, H Malmgren, et al.
Pages: 900 - 908 - Prevalence and architecture of de novo mutations in developmental disorders(2017)
Authors: The Deciphering Developmental Disorder Study, Stephen Clayton, Tomas W Fitzgerald, Joanna Kaplanis, Elena Prigmore, Diana Rajan, Alejandro Sifrim, Stuart Aitken, Nadia Akawi, Mohsan Alvi, et al.
Pages: 433 - + - Recent advances in congenital heart disease genomics(2017)
Authors: Alejandro Sifrim
Pages: 869 - Interpretation and Prioritization of Genomic Single-Nucleotide Variation(2016)
Authors: Alejandro Sifrim, Yves Moreau, Joris Vermeesch, Jan Aerts
- Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing(2016)
Authors: Alejandro Sifrim, Jeroen Breckpot, Bernard Thienpont, Marc Gewillig, Jacoba Louw, Koenraad Devriendt
Pages: 1060 - +