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Structure of a transporter domain emerges
Journal Contribution - Journal Article
Magnesium homeostasis relies on transporters like the CNNM family, but little information on these proteins' structure and regulation limits our understanding of their biology and functions in disease. New characterization of a conserved cytoplasmic domain now confirms the presence of a self-liganded architecture that is indispensable for Mg2+ efflux and suggests a possible role for a dimeric assembly.
Journal: Journal of Biological Chemistry
Pages: 20008 - 20009
Number of pages: 2