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Structure of a transporter domain emerges

Journal Contribution - Journal Article

Magnesium homeostasis relies on transporters like the CNNM family, but little information on these proteins' structure and regulation limits our understanding of their biology and functions in disease. New characterization of a conserved cytoplasmic domain now confirms the presence of a self-liganded architecture that is indispensable for Mg2+ efflux and suggests a possible role for a dimeric assembly.
Journal: Journal of Biological Chemistry
ISSN: 0021-9258
Issue: 52
Volume: 293
Pages: 20008 - 20009
Number of pages: 2
Publication year:2018