< Back to previous page

Publication

Specific Imaging of CD8+ T-Cell Dynamics with a Nanobody Radiotracer against Human CD8β

Journal Contribution - Journal Article

While immunotherapy has revolutionized the oncology field, variations in therapy responsiveness limit the broad applicability of these therapies. Diagnostic imaging of immune cell, and specifically CD8+ T cell, dynamics could allow early patient stratification and result in improved therapy efficacy and safety. In this study, we report the development of a nanobody-based immunotracer for non-invasive SPECT and PET imaging of human CD8+ T-cell dynamics.
Journal: Eur J Nucl Med Mol Imaging
ISSN: 1619-7070
Publication year:2024
Keywords:Radiology & nuclear medicine
  • ORCID: /0000-0001-7359-1751/work/172848309
  • Scopus Id: 85202920368
  • WoS Id: 001302076900001
  • ORCID: /0000-0002-4442-7474/work/171148567
  • ORCID: /0000-0002-9065-1549/work/171148738
  • ORCID: /0000-0001-9220-4833/work/171149161
  • ORCID: /0000-0001-6918-2955/work/171151118
  • ORCID: /0009-0000-1795-3957/work/171151448
  • DOI: https://doi.org/10.1007/s00259-024-06896-3
Accessibility:Open

Authors/publisher

Research units