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Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli O104:H4 strain from the 2011 outbreak in Germany
Journal Contribution - Journal Article
In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak strain could be selected rather easily from a phage bank or isolated from the environment. It is argued that phage therapy should be more considered as a potential armament against the growing threat of (resistant) bacterial infections.
Journal: PLOS ONE
ISSN: 1932-6203
Issue: 12
Volume: 7
Pages: e52709
Publication year:2012
Keywords:Bacteriolysis, Bacteriophages, Disease Outbreaks, Escherichia coli Infections, Germany, Hemolytic-Uremic Syndrome, Humans, Open Reading Frames, Shiga-Toxigenic Escherichia coli
- See also: Selection and Characterization of a Candidate Therapeutic Bacteriophage That Lyses the Escherichia coli O104:H4 Strain from the 2011 Outbreak in Germany
- See also: Selection and characterization of a candidate therapeutic bacteriophage that lyses the Escherichia coli O104:H4 strain from the 2011 outbreak in Germany
- See also: Selection and characterization of a candidate therapeutic bacteriophage that lyses the **Escherichia coli** O104:H4 strain from the 2011 outbreak in Germany