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Publication

Online detection of tonic-clonic seizures in pediatric patients using ECG and low-complexity incremental novelty detection

Book Contribution - Book Abstract Conference Contribution

Home monitoring of refractory epilepsy patients has become of more interest the last couple of decades. A biomedical signal that can be used for online seizure detection at home is the electrocardiogram. Previous studies have shown that tonic-clonic seizures are most often accompanied with a strong heart rate increase. The main issue however is the strong patient-specific behavior of the ictal heart rate features, which makes it hard to make a patient-independent seizure detection algorithm. A patient-specific algorithm might be a solution, but existing methods require the availability of data of several seizures, which would make them inefficient in case the first seizure only occurs after a couple of days. Therefore an online method is described here that automatically converts from a patient-independent towards a patient-specific algorithm as more patient-specific data become available. This is done by using online feedback from the users to previously given alarms. By using a simplified one-class classifier, no seizure training data needs to be available for a good performance. The method is already able to adapt to the patient-specific characteristics after a couple of hours, and is able to detect 23 of 24 seizures longer than 10s, with an average of 0.38 false alarms per hour. Due to its low-complexity, it can be easily used for wearable seizure detection at home.
Book: 37th Annual International Conference of the IEEE Engineering in Medicine, and Biology Society (EMBC), AUG 25-29, 2015, Milan, ITALY
Pages: 5597 - 5600
Publication year:2015
Keywords:P1 Proceeding
BOF-keylabel:yes
Authors from:Government
Accessibility:Closed