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Low cycle threshold value in Xpert MTB/RIF assay may herald false detection of tuberculosis and rifampicin resistance: a study of two cases

Journal Contribution - Journal Article

We report 2 cases for whom Xpert MTB/RIF falsely signaled rifampicin-resistant tuberculosis, based on unusually low cycle threshold and 3 of 5 probes missing. Other mycobacterial tests were negative. Further optimization of the Xpert MTB/RIF algorithm is warranted.

Journal: Open Forum Infectious Diseases
Issue: 2
Volume: 8
Number of pages: 5
Publication year:2021
Keywords:active case finding, false detection of TB, rifampicin resistance, Xpert MTB/RIF assay