< Back to previous page

Publication

Clinical implementation of DeepVoxNet for auto-delineation of organs at risk in head and neck cancer patients in radiotherapy

Book Contribution - Book Chapter Conference Contribution

© Springer Nature Switzerland AG 2018. Delineation of organs at risk (OAR) on CT images is a crucial step in the planning of radiotherapy treatment. Manual delineation is time-consuming and high interrater variability is observed within and across radiotherapy centers. Automated delineation of OAR is fast and can lead to more consistent treatment plans. We developed an auto-delineation tool based on a 3D convolutional neural network (CNN) to automatically delineate 16 OAR structures in head and neck cancer (HNC) patients. The CNN was trained off-line using 70 previously collected patient datasets and implemented to be available on-line in clinical routine practice. The tool was applied prospectively for delineation of 20 consecutive new HNC cases within the department of Radiation Oncology, with subsequent manual editing and approval of the contours by the clinical expert. Validation based on the automatically proposed and edited contours shows that the auto-delineation tool is able to achieve highly accurate segmentation results for most OAR. As a result, 3D delineation time is reduced to less than 19 min on average (about 1 min/structure), compared to usually 1 h or more without auto-delineation tool.
Book: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages: 223 - 232
ISBN:9783030012007
Publication year:2018
BOF-keylabel:yes
IOF-keylabel:yes
Authors from:Higher Education
Accessibility:Open