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Cell surface ABP1-TMK auxin-sensing complex activates ROP GTPase signaling

Journal Contribution - Journal Article

Auxin-binding protein 1 (ABP1) was discovered nearly 40 years ago and was shown to be essential for plant development and morphogenesis, but its mode of action remains unclear. Here, we report that the plasma membrane-localized transmembrane kinase (TMK) receptor-like kinases interact with ABP1 and transduce auxin signal to activate plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading to changes in the cytoskeleton and the shape of leaf pavement cells in Arabidopsis. The interaction between ABP1 and TMK at the cell surface is induced by auxin and requires ABP1 sensing of auxin. These findings show that TMK proteins and ABP1 form a cell surface auxin perception complex that activates ROP signaling pathways, regulating nontranscriptional cytoplasmic responses and associated fundamental processes.
Journal: SCIENCE
ISSN: 0036-8075
Issue: 6174
Volume: 343
Pages: 1025 - 1028
Publication year:2014
BOF-publication weight:10
CSS-citation score:3
Authors from:Higher Education