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Publication
Blood platelet biochemistry
Journal Contribution - Journal Article
Defects in platelet function or formation increase the risk for bleeding or thrombosis, which indicates the crucial role for platelets in maintaining haemostasis in normal life. Upon vascular injury, platelets instantly adhere to the exposed extracellular matrix which results in platelet activation and aggregation and the formation a haemostatic plug that stops bleeding. To prevent excessive platelet aggregate formation that eventually would occlude the vessels, this self-amplifying process nevertheless requires a tight control. This review intends to give a comprehensive overview of the currently established main mechanisms in platelet function.
Journal: THROMBOSIS RESEARCH
ISSN: 0049-3848
Issue: 3
Volume: 129
Pages: 245 - 249
Publication year:2012
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:1
CSS-citation score:2
Authors from:Higher Education
Accessibility:Closed
- See also: Blood platelet biochemistry