An in vitro and ex vivo Study on the Expression and Role of Dipeptidyl Peptidase 9 in the Lung.

This project fits in the study of the role and expression of DPP9 in lung pathophysiology with an emphasis on lung fibrosis. However, DPP9 is part of a larger family of DPPs with structural similarities and overlapping substrate specificities. Initially, we want to establish a DPP atlas of the lung to provide context to the study of DPP9 specifically. Our second and main objective is to form a picture of DPP9's role and expression in the lung, starting from our current knowledge of DPP9 in human macrophages, towards a broader take on DPP9 and lung fibrosis.

Keywords:DIPEPTIDYL PEPTIDASE

Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences