Unraveling the role of BK polyomavirus variants and of cellular CMP kinase on viral pathogenicity and clearance in renal-transplant patients (RENAL-TRANSPLANT)

The results obtained with our project provide the possibility for doctors who treat BKPyV reactivation in renal transplant patients to classify the patients according to the risk of viremia development and the sensitivity to cidofovir-based treatment. The genotypic characterization of the BKPyV strain and the cellular CMP kinase gene can identify which subgroup of patients is in at risk and which may benefit from treatment.