Unraveling the molecular basis and genetic epidemiology of Charcot-Marie-Tooth neurpathies: contribution from Northeast Brazil.

In this study we aim to deliver a better understanding of the molecular basis and genetic epidemiology of CMT by finding novel causative genes and performing genotype-phenotype correlations, as they offer partical advantages form a biological and translational perspective. Our unique entry point is an ethnically diverse collection of families and sporadic patients from Northeast Brazil, a geographic area not representied on the epidemiological map of Charcot-Marie-Tooth.

Keywords:BRAZIL, CHARCOT-MARIE-TOOTH DISEASE, NEUROPATHIES

Disciplines:Genetics, Systems biology, Laboratory medicine, Medical systems biology, Molecular and cell biology