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Project
Towards an Atlas of Human Genomic Imprinting
Imprinting refers to mono-allellic expression of genes. It is involved in developmental disorders and in tumor development. As the extend of imprinting in human is currently unknown, we will use RNA-sequencing to generate a comprehensive atlas of imprinted genes and parental origins of the expressed alleles. This will be of great value in the interpretation of genome wide data, from techniques such as microarray and whole exome sequencing.
Date:1 Feb 2014 → 31 Dec 2014
Keywords:HEREDITARY, GENETIC DISEASE, GENETIC SCREENING, EPIGENETICS
Disciplines:Scientific computing, Bioinformatics and computational biology, Genetics, Systems biology, Molecular and cell biology, Public health care, Public health services