< Back to previous page
Project
Study of an innovative strategy to deliver drugs into the brain based on naturally occurring extracellular vesicles.
Drug delivery to the brain is still problematic due to the presence of brain barriers such as the blood-cerebrospinal fluid barrier, formed by the choroid plexus epithelial cells. We found that extracellular vesicles, produced by these cells, penetrate the brain. Here, we aim to unravel the mechanism and study whether these extracellular vesicles have potential as therapeutic delivery system.
Date:1 Jan 2017 → 31 Oct 2021
Keywords:blood-brain barrier, extracellular vesicles, drug delivery
Disciplines:Pharmaceutics, Neurosciences, Drug discovery and development, Cognitive science and intelligent systems, Toxicology and toxinology, Pharmacognosy and phytochemistry, Biological and physiological psychology, Medicinal products, Pharmacotherapy, Other pharmaceutical sciences, Biomarker discovery and evaluation, Pharmacology, Developmental psychology and ageing