Solid phase synthesis of functional RAFT chain transfer agents: towards the design of well defined building blocks for multivalent supramolecular nanoassemblies

Nanoengineered structures with dimensions below 1 µm are highly attractive for targeted delivery of a therapeutic payload to specific cells and tissues. We aim in this project to develop a generic strategy for the synthesis of polymeric nanocarriers that expose multivalent ligands on their surface based on an innovative approach for the synthesis of polymers with a multivalent functional end-group.