SLEEP-TO-MOVE: Boosting rehabilitation through sleep-based interventions in Parkinson’s disease

People with Parkinson’s disease (PD) present difficulty consolidating newly learned skills into long-term memory, which reduces the benefits of training. Sleep facilitates motor memory consolidation, especially in combination with targeted memory reactivation (TMR). TMR works by adding associated sounds during learning that are replayed during sleep. Consolidation during sleep may be preserved in PD, but robust findings are lacking and have not involved TMR. Here I address this imperative by investigating the effect of napping on motor memory consolidation by experimentally manipulating exposure to sleep and TMR in PD for the first time.

Keywords:Parkinson's disease, Rehabilitation, Sleep

Disciplines:Rehabilitation, Sleep medicine