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The role of vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) in the pathophysiology of the hepatopulmonary syndrome (3F020014)

Hepatopulmonary syndrome (HPS), a complication of liver disease, is characterized by impaired gas exchange and results in increased morbidity and mortality. The role of angiogenesis in the pathogenesis of HPS will be studied by using a mouse model. Besides, a clinical multicenter study with Eurotransplant will be set up, focusing on HPS and portopulmonary hypertenstion in the setting of transplantation.

Date:1 Oct 2014  →  30 Sep 2018
Keywords:Hepatopulmonary syndrome, liver disease
Disciplines:Gastro-enterology and hepatology