The role of the innate immune system in neurodegeneration and neuroprotection.

A neurodegenerative respons in peripheral axons tends to trigger an innate immune response in Schwann cells. In this project we would like to explore the precise role of this response and how it contributes to nerve regeneration and remyelination on one hand or - in cases where it gets out of control - to neurodegeneration on the other hand. A better understanding of these processes will allow us to manipulate and use this inherent capacity of our body for nerve protection and nerve regeneration in future therapies.

Keywords:INNATE IMMUNITY, NEUROPROTECTION, NEURODEGENERATION

Disciplines:Immunology, Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing