Protection of chickens against a broad range of Salmonella serotypes by the use of colonization-inhibition attenuated strains with defined living attenuated strains

The aim of the project is to create live attenuated Salmonella strains, which protect broiler chickens after oral administration against colonization by Salmonella. These colonization-inhibition (CI) strains are produced by introducing mutations into the genome so these strains can no longer persist in the broiler, while maintaining protection against colonization.