Prenatal adeno-associated viral transduction of the enteric nervous system as a novel toolbox in neurogastroenterological research.

The enteric nervous system (ENS) is responsible for the regulation of basic gastrointestinal functions and harbors different subtypes of neurons, difficult to identify in (live cell) experiments. This research project studies the prenatal transduction of the ENS with recombinant adeno-associated viral vectors with the goal of employing this methodology for the identification, modulation and imaging of functional neuronal subtypes during the development of the ENS.

Keywords:GASTROINTESTINAL DEVELOPMENT, ENTERIC NERVOUS SYSTEM, RESEARCH METHODOLOGY, ADENO ASSOCIATED VIRUS

Disciplines:Gastro-enterology and hepatology, Morphological sciences