New alternative carcinogenic prediction assay using flatworm stem cell proliferation patterns. (R-7830)

Flatworms are promising model organisms for cancer research because of their experimentally accessible stem cells and remarkable regeneration capacity. Previously, we developed a non-mammalian, in vivo carcinogenic assay, which has the potential to bridge the gap between in vitro /cellular assays and mammalian models in carcinogenicity screenings. In the 'proof of concept'-project, we will validate the assay by increasing the number of tested compounds. Target markets and valorization strategies will be explored to in function of further implementation of our stem-cell-based assay.

Keywords:flatworm

Disciplines:Evolutionary biology