Modulation of Memory-Related Brain Networks with Non-Invasive Brain Stimulation: A Multimodal Neuroimaging Investigation

Motor memory consolidation is supported by the dynamical interaction between striato- and hippocampo-cortical networks (1-3). However, it remains unknown whether these networks can be modulated in order to influence consolidation. The aim of this project is to use an innovative and comprehensive multimodal approach in order to investigate whether non-invasive brain stimulation (NIBS) can be used to modulate the interaction between these memory-relevant brain networks. Specifically, we will use state-of-the-art neuronavigated transcranial magnetic stimulation, tailored to each individual, in combination with both resting-state and task-related magnetic resonance imaging and spectroscopy, in order to capture the underlying NIBS effects on neural activity, functional connectivity and concentration of relevant neurometabolites in memory-related networks.

Keywords:Motor learning, Memory consolidation, Neuroimaging, Brain stimulation, Hippocampus, Striatum

Disciplines:Education curriculum