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Project

Late-Stage Peptide Modification via C-H Activation

Part one involves Ru-catalyzed intermolecular annulation reactions for the late-stage peptide diversification through C-H activation, using an internal peptide amide group as directing group. The second part deals with Pd-catalyzed cross-coupling reactions for the late-stage peptide diversification through C-H activation, using an internal peptide amide group as directing group.
Date:1 Oct 2019  →  Today
Keywords:peptides, C-H activation, annulation, ruthenium, palladium
Disciplines:(Bio)molecular modelling and design