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Improved human iPS generation by targeting the reprogrammingsfactors in an inducible and exchangeable way within the human ROSA26 locus via ZFN

We want to optimize an advanced method to generate human induced pluripotent stem cells (iPS) by targeting the reprogramming factors to the human ROSA26 locus via Zinc Finger Nuclease (ZFN) technology.

Date:1 Jan 2012 →  31 Dec 2014
Keywords:ZFN, iPS, stem cells
Disciplines:Other (bio)medical engineering, Biological system engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering, Biomaterials engineering, Biomechanical engineering