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Project

Functional analysis of the role of post-translational modifications of TPLATE Complex subunits for clathrin-mediated endocytosis in plants

We recently identified the TPLATE complex as an essential factor for plant clathrin-mediated endocytosis. This complex is evolutionary ancient but apparently lost in ophistokonts. Aim of this project is to unravel the function of post-translational modifications occurring in the subunits of this octameric protein complex. Their functionality will be addressed by live cell imaging, mutant complementation and protein purification assays.

Date:1 Jul 2015 →  30 Sep 2019
Keywords:clathrin-mediated endocytosis, protein complex purification, TPLATE complex, plant cell biology
Disciplines:Plant biology, General biology