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Flexible Multi Electrode Array for electrical cellular interfacing

Silicon is a suitable material for electrically interfacing with biological cells and tissues. However due to silicon’s high modulus and hardness relative to biological tissues, limits appear in an ability to recapitulate cellular systems in vitro. The focus here is the physical design and development of a multi electrode array that features global mechanical properties similar to in vivo tissue. Additional features may be explored such as fluidics for media prefusion, fluid pressure control, three-dimensional arrays, and hydrogel integration.

Date:23 Jan 2019  →  Today
Keywords:Silicon, Electrode, Cellular Scaffold, Organ-on-chip, Neuronal Cells, Cellular Impedence, Cellular Stimulation
Disciplines:Cellular interactions and extracellular matrix, Nanobiotechnology, Micro- and nanoelectromechanical systems, Molecular and cellular biomechanics, Cell, tissue and organ engineering, Neurosciences not elsewhere classified
Project type:PhD project