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Fetal cell isolation and characterization for cell-based non-invasive prenatal genetic diagnosis (01D26517)

Size-exclusion micro-fluidic technology will be developped to capture fetal trophoblasts from maternal peripheral blood, allowing downstream massively parallel sequencing analyses. These methods can be used to develop non-invasive prenatal testing (NIPT) providing diagnoses that can currently only be obtained by invasive techniques.

Date:1 Oct 2017  →  Today
Keywords:Cell-based non-invasive prenatal diagnosis (NIPT), massively parallel sequencing, liquid biopsy, rare cell isolation from blood
Disciplines:Molecular and cell biology, Oncology, Diagnostics, Systems biology, Laboratory medicine, Medicinal products, Morphological sciences, Genetics