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Project

Fatty acid metabolism as a key mediator of therapy resistance in BRAF-mutant malignant melanoma.

This project will explore the potential of a new strategy to treat Hepatocellular carcinoma (HCC). This strategy involves the combination of cyclotoxic agents, which are currently applied in the clinic but in monotherapy insufficient to provice longlasting remission, with agents targeting the adaptive mechanisms of a recently identified tumour cell subpopulation presumably responsible for chemoresistance and relapse.

Date:1 Jan 2017 →  31 Dec 2018
Keywords:Fatty acid metabolism, therapy resistance, BRAF-mutant malignant melanoma
Disciplines:Morphological sciences, Oncology