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Project

Dynamic modulation of disease progression in chronic gut and joint inflammation in spondyloarthritides

In this proposal the relation between gut and joint inflammation in spondyloarthritis is investigated by examininng the underlying cellular and molecular mechanisms of inflammation with focus on mechanical strain and immune regulation. Through miniature ecosystems, i.e. pre-adapted microbial cocktails, we aim to boost immune regulatory mechanisms thereby altering the disease course.

Date:1 Jan 2017 →  31 Oct 2022
Keywords:spondyloarthritis, microscopic gut inflammation, biomechanical stress
Disciplines:Orthopaedics, Gastro-enterology and hepatology