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Dissecting the regulatory dynamics that govern Kupffer cell differentiation (01IO4716)

We aim to unravel the regulatory dynamics underlying Kupffer-cell differentiation. By combining expertise in computational modeling (Dambi group) and self-generated experimental mouse models (Onset group) we will design new data mining algorithms that will allow to model Kupffer-cell differentiation from high-throughput single-cell datasets. Importantly, our novel mouse models will allow the in vivo validation of these in silico predictions.

Date:1 Oct 2016  →  Today
Disciplines:Other clinical sciences, Regenerative medicine, Laboratory medicine, Palliative care and end-of-life care, Other basic sciences, Other medical and health sciences, Other health sciences, Nursing, Other translational sciences, Other paramedical sciences