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Project

Development of an oral vaccine to protect pigs against postweaning diarrhoea caused by F4+ enterotoxigenic EScherichia coli

In this project, an oral vaccine will be developed to protect pigs against F4+ E. coli induced postweaning diarrhoea. Therefore, the F4 protein or DNA will be encapsulated in nanoparticles to prevent gastro-intestinal degradation and specific lectins will be used to promote uptake through the epithelial barrier via enterocytes or M cells.

Date:1 Feb 2008 →  31 Jan 2010
Keywords:pigs, postweaning diarrhoea, oral vaccination
Disciplines:Microbiology, Immunology