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Project
Design and synthesis of TSLP complex antagonists based on chemo- and bio-informatics.
Atopic diseases represent an important unmet need in modern day medicine. The pro-inflammatory cytokine TSLP is a key player in these pathologies. The aim of this project is the development of small molecules capable of disrupting TSLP signalling, using a chemo-and bio-informatics approach. These small molecules could help elucidate the role of TSLP in various pathologies and could be a starting point for further development of drugs targeting this pathway.
Date:1 Jan 2015 → 31 Dec 2015
Keywords:COMPUTATIONAL MODELS, ATOPIC DISEASE, BIOINFORMATICS
Disciplines:Laboratory medicine, Medical systems biology, Medicinal chemistry