Characterizing a rupture-prone mouse model of aortic aneurysm: the road to post-mortem validation of AAA rupture risk predicted by biomechanical computational models

Abdominal aortic aneurysm (AAA) is a local dilatation of the aorta that can lead to sudden death when it ruptures. Patients are currently operated when the aneurysmatic diameter exceeds 5.5 cm. In this project, we want to investigate whether numerical techniques can characterize and predict the actual rupture incidence and location in a novel, rupture-prone mouse model of the disease.