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Project

Characteristic glycosylation patterns displayed on porcine reproductive and respiratory syndrome virus (PRRSV) and PRRSV-infected cells and their role in interactions with sialic acid-binding immune system lectins

Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen of swine. This research project aims to analyze the nature of the virus-linked glycans and the influence of PRRSV infection on cellular glycosylation. Furthermore, the interaction of these glycans with sialic acid-binding immune system lectins will be analyzed, as these are often crucial in regulation of immune responses.

Date:1 Oct 2011 →  30 Sep 2014
Keywords:immune system lectins, PRRSV, glycosylation
Disciplines:Microbiology, Systems biology, Immunology, Laboratory medicine