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Project

Association between different measures of global and local adiposity with clinico-pathological features, circulating markers, lipidomic profiles and outcome in postmenopausal breast cancer patients treated in the IBCSG 35-07 (SOLE)/BIG 1-07 trial

We will aim at investigating the association between different measures of global (BMI) and local (CLS and size of adipocytes) adiposity with clinico-pathological features and outcome in 3000 early postmenopausal breast cancer patients treated in the IBCSG 35-07 (SOLE/BIG 1-07 trial. Additionally we will explore plasmatic circulating endocrine and inflammatory markers together with lipidomic profiles before and during treatment in 100 of these patients to further enhance our understanding of the systemic effects of global and local adiposity

Date:1 Jan 2019 →  31 Dec 2021
Keywords:adiposity, postmenopausal breast cancer
Disciplines:Cancer prevention