Acute-on-chronic liver failure (ACLF): monocyte profiles as a predictor for progression or recovery signatures in patients.

We aim to study the dynamics of the monocyte activation status during the course of ACLF, and assess how this associates with disease outcome. By doing paired transcriptional and functional analysis of monocytes isolated at different time-points form recently diagnoses ACLF patients, we aim to profile survivors and non-survivors.