Substituted indole derivatives as dengue viral replication inhibitors

The present invention concerns substituted indole derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

Patent Publication Number: US10646469

Year filing: 2020

Year approval: 2020

Year publication: 2020

Status: Assigned

Technology domains: Pharmaceuticals

Validated for IOF-key: Yes

Attributed to: Associatie KULeuven