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Patent

RESISTANCE TO OXIDATIVE STRESS

The disclosure relates to diagnosis and/or prognosis of type 2 diabetes (T2DM) in relation to obesity and prediction of response to treatment for T2DM. The determination of a patient's risk of developing T2DM and/or the prediction of a subject's response to treatment for T2DM is based on a biomarker profile comprising at least one of the genes COX4I1, COX10, PTGS1, PTGS2, and SOD2. The gene(s) may be measured in monocytes, or microvesicles derived from monocytes, or cells derived from white or brown adipose tissues.
Patent Publication Number: WO2015081391
Year filing: 2014
Year approval: 2016
Year publication: 2015
Status: Requested
Technology domains: Biotechnology
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven