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The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo.
Patent Publication Number: US8852554
Source: USPTO
Year filing: 2010
Year approval: 2014
Year publication: 2014
Status: Assigned
Technology domains: Measurement, Pharmaceuticals
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven